OSAKA UNIVERSITY SHORT-TERM STUDENT EXCHANGE PROGRAM _

Objective
This course gives foreign students an introduction to chemical, biological, and environmental pharmaceutical sciences and their recent progress in Japan. This course is primarily intended for international graduate students from other disciplines in the Faculty of Pharmaceutical Sciences, but we reform it suitable to undergraduate students in the short-term student exchange program.

Textbook
No particular text book is used. Some materials will be distributed in the class.

Lecture Outline

Week 1.	An introduction to pharmaceutical sciences in the Faculty (Guidance)
Week 2.	Environmental toxicology Diseases produced by environmental pollutants in Japan
Week 3.	Molecular toxicology Molecular mechanisms of biological responses to environmental pollutants
Week 4.	Molecular medicine Molecular biology of atherosclerosis
Week 5.	Technical tour and discussion Facilities concerning environmental systems
Week 6.	Biophysical Chemistry Structure of bioactive macromolecule
Week 7.	Synthetic organic chemistry Strategies for synthesis of biologically active natural products
Week 8.	Analytical chemistry Importance of analytical chemistry in development of new medicines
Week 9.	Modern instrumentation (Laboratory demonstration) Theory and practice of modern instrumental techniques in chemical analysis
Week 10.	Neuroimmunology Environmental or emotional stress alters immune responses
Week 11.	Gene therapy Development of fusogenic liposome and application for genetherapy
Week 12.	Production of medicine by cell culture Microbial production of antibiotics; large-scale cultivation of animal cells; use of recombinant DNA technology
Week 13.	Laboratory demonstration and discussion Cultivation of microorganisms; demonstration of antibiotic titer
Week 14-15.	Final examination (Term paper preparation)