05f-11
INTRODUCTION TO PHARMACEUTICAL SCIENCES

Katsuji TANI, Shunji AOKI, Naoyoshi MAEZAKI, Tadayasu OHKUBO, Yasuhiro KOHAMA, Kiyohito YAGI, Ayako KOBAYASHI, Shinsaku NAKAGAWA, Tatsuya TAKAGI, Norio ITOH, and Jun-ichi NISHIKAWA (Graduate School of Pharmaceutical Sciences)

Objective
This course provides an introduction to pharmaceutical sciences from chemical, biological and environmental perspectives and includes a review of recent advances in Japan. This course consists of lectures, demonstration of experiments and discussions with teachers and graduate students.

Textbook
No particular textbook is used, but some materials will be given out in class.

Lecture Outline
1. Introduction Assoc. Prof. Tani
2. Drugs from the nature Assoc. Prof. Aoki
3. Chemical structure and biological activity Assoc. Prof. Maezaki
4. Structure based rational drug design Assoc. Prof. Ohkubo
5. Cellular mechanisms underlying cancer and stroke Assoc. Prof. Koyama
6. Production of pharmaceuticals by cell culture Prof. Yagi
7. Utilization of insect and nematode for pharmaceutical research Assoc. Prof. Kobayashi
8. DDS technology for gene therapy Assoc. Prof. Nakagawa
9. Drug Design using Molecular Graphics Prof. Takagi
10. Introduction to toxicology Assoc. Prof. Itoh
11. Effects of environmental pollutants on endocrine system Assoc. Prof. Nishikawa
12. Demonstration of some experiments on pharmaceutical sciences

Grading
The course grade will be based on a term paper to be submitted at the end of the course (60%) and class participation & discussion (40%).